If Vegas sounds overwhelming and you're looking for a more relaxing vacay for Memorial Day weekend, consider Sea Island, Ga. It's easy to get to, especially from the East Coast by flying into Jacksonville and renting a car for the quick hour or so drive to Georgia. The wide avenues and Spanish moss hanging from the banyan trees will put you in that laid back Southern mood right away.
We'd recommend a stay at the Cloister where guests are encouraged to "do everything or nothing at all." Perfect! If you can gather a larger group of girlfriends, consider renting one of the two or three bedroom villas which have spacious living rooms and kitchens.
When you're there don't miss the Cloister Spa, which is in our top-five most lux spas we've ever visited and we're not alone: Forbes, Mobil and SpaFinder have all ranked very high. It has a curving stream which winds through the huge 65,000 square foot facility.
There are five restaurants on the property and shopping nearby. We'd be lounging by the pool or walking on the beach; but there are also golf courses everywhere, if you're ready to hit some balls. You can expect great weather in Georgia this time of year, so enjoy!